MyVariant.info

Variant Annotation as a Service

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Requests in the last 30 days

Service Status

Last Updated Nov 22 2024

Month Status

Uptime for 1/*

*Data collection in progress. Some dates might be unavailable
* Monitored every 5 minutes
CIViC
NCATS
PHARMGKB
OMNI
VAPR
Open Humans
MyGene2
ClinGen

High performance

Fast API Access to Up-to-Date Variant Annotations

Up-to-date

Weekly Updated Variant Annotations from 19 Sources.

Pre-integrated

Variant annotations for >400M human variants are pre-integrated.

Simple to use

Just two end-points to retrieve annotations via HGVS IDs or any query term.

    TRY IT

    HTTP HTTPS
    GET
    Retrieving by HGVS id
    https://myvariant.info/v1/variant/chr7:g.55241707G>T
    GET
    All variants with clinvar annotation
    https://myvariant.info/v1/query/?q=_exists_:clinvar
    GET
    All non-synonymous variants on gene "BTK"
    https://myvariant.info/v1/query/?q=dbnsfp.genename:BTK
    GET
    All variants within a genomic range
    https://myvariant.info/v1/query/?q=chr1:69000-70000
    GET
    Query Wellderly variants together with other annotation sources
    https://myvariant.info/v1/query/?q=_exists_:wellderly AND cadd.polyphen.cat:possibly_damaging&fields=wellderly,cadd.polyphen
    GET
    Get data source metadata
    https://mygene.info/metadata/
    GET
    Get the list of all fields
    https://mygene.info/metadata/fields
    Batch queries OK
    POST http://myvariant.info/v1/variant POST http://myvariant.info/v1/query

What's New

Medical Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

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